Shahriar Koochekpour, MD, PhD

Professor of Oncology
Departments of Cancer Genetics, Medicine and Urology
Roswell Park Cancer Institute
Professor of Cell and Molecular Biology
University at Buffalo

Dr. Koochekpour joined the staff of Roswell Park Cancer Institute (RPCI) as an Associate Professor of Cancer Genetics, Urology and Oncology in 2011. Dr. Koochekpour graduated from Shiraz Medical School, Shiraz University of Health Sciences Center (Iran), with an MD degree and followed that with a short-term residency in General Pathology. Dr. Koochekpour obtained his PhD in cellular and molecular oncology from Kings College School of Medicine, University of London; London, UK. He continued his postdoctural training at the National Cancer Institute-Advanced Bioscience Laboratories, Frederick Cancer Research and Development Center, Frederick, Maryland.  Dr. Koochekpour has comprehensive training and experience in cellular and molecular biology of cancer, analyzing gene expression and functions, oncogenes and tumor suppressors, genetics, health disparity and translational cancer research.

Research Interests: 
Identifying soluble, genetic or epigenetic biomarkers of prostate cancer aggressiveness and progression
Elucidating biological mechanisms underlying androgen receptor-dependent signaling and androgen-independent progression of prostate cancer
Developing molecular targeted therapy for metastatic castrate-resistant prostate cancer
Identifying biological factors and molecular mechanisms responsible for disparities at presentation, aggressiveness and progression, treatment, and outcome in African-American men affected by prostate cancer
Defining the clinicohistopathological significance of metabotropic glutamate receptor 1 (mGluR1 or GRM1) in prostate carcinogenesis and its androgen-independent or metastatic progression
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