James Marshall, PhD

Distinguished Professor Emeritus
Roswell Park Cancer Institute

Dr. James R. Marshall joined the faculty of Roswell Park Cancer Institute (RPCI) in 2002 as Senior Vice President for Cancer Prevention and Population Sciences, and Chair of the Department of Cancer Prevention and Population Sciences. He came to RPCI from Arizona Cancer Center, Tucson, where since 1996, he served as Associate Director of Cancer Prevention and Control and Professor of Public Health and Medicine at the University of Arizona College of Medicine.

Dr. Marshall earned his doctoral degree in Sociology from the University of California at Los Angeles in 1977. He joined the faculty of the Department of Sociology at the University at Buffalo (UB) where he served until 1981. From 1981 to 1996, Dr. Marshall was a faculty member of the Department of Social and Preventive Medicine, School of Medicine & Biomedical Sciences rising in rank from Assistant to Full Professor (1981-1983), and the School of Health-Related-Professions (1991-1996), both at UB.

Dr. Marshall’s research interests focus on the identification and testing of chemoprevention strategies in human populations; evaluating diet as a means of preventing breast cancer recurrence; epidemiologic analysis of predictors of genetic mutation in adenomatous polyps; familial colon cancer registries; and independent associations between diet and breast and endometrial cancers.

Dr. Marshall is a member of a number of professional organizations, including the American Association for Cancer Research, the American Epidemiologic Society, the American Society of Preventive Oncology, American Society for Clinical Oncology and the Society for Epidemiologic Research.

Dr. Marshall is Chair, the Cancer Prevention Committee of the Alliance for Clinical Trials in Oncology, and, until recently a panel member of the NIH/NCI IRG Parent Committee for Cancer Center Support Grants. He is an external advisor to the Knight Cancer Center, Oregon Health and Science University; the Simmons Cancer Center, University of Texas Southwestern Medical Center; the Moffitt Cancer Center, University of South Florida; and the University of Illinois Chicago Cancer Center and Carbone Cancer Center, University of Wisconsin.

Dr. Marshall has authored or co-authored more than 260 journal publications, book chapters and abstracts. He is an Associate Editor for Oncology; Cancer Epidemiology, Biomarkers & Prevention; and Cancer Prevention Research (CaPR).

Research Program
Three major components to this research:

  1. Nutrition and cancer: We suspect that diet is related to cancer risk, but our results to date have been equivocal. We are trying to identify barriers to understanding this problem.

  2. Use of biomarkers to measure chemoprevention efficacy: We are especially interested in characteristics of neoplastic but not yet malignant lesions that might reflect progression toward or regression from malignancy.

  3. Molecular epidemiology: Use of molecular characteristics of tumors as a possible key to their etiology, as well as consideration of genetic polymorphisms as they affect the association of environmental exposures and cancer risk.
Research Interests: 
Diet modification and prostate cancer progression
Identification and testing of chemoprevention strategies in human populations
Evaluating diet as a means of preventing breast cancer recurrence
Epidemiologic analysis of predictors of genetic mutation in adenomatous polyps
Familial colon cancer registries
Independent associations between diet and breast and endometrial cancers