Trends in Tumor Immunology

Course ID: 
MIR 509

General Class Notes:

This course requires, as a pre-requisite, an upper level General Immunology course. If you do not have a strong background in Immunology, you will have difficulty with the material covered.


This is a 2 credit hour course. The first part of the course will be composed of 9 lectures and required reading assigned by faculty on specific advanced topics in tumor immunology. This section is followed by an in-class, essay/short-answer exam worth 50% of your grade.

The second part of the course will be composed of individual student oral presentations (via PowerPoint; approximately 30 minutes each) that summarize detailed, well-organized information from a recent review article in Tumor Immunology. The review articles will be provided to all students to choose from on the first day of class. This presentation is worth 40% of your grade.

This course will also include a discussion of Medical Ethics and aspects of professional and responsible career development. Further, there will be time devoted to topics in professional career development in research within many classes. Participation in this section of the class is worth 10% of your grade.

Attendance Policy

Classes are held Wednesdays from 3-5 PM in CGP L5-130. Students are expected to attend all classes and participate with discussion and questions. Students are expected to be on time for each lecture. Unexcused absence from class will result in a 10% reduction in overall grade for each class missed. There will be no make-up exams unless there is a confirmed illness (students must have an excuse from a local doctor).

Questions or Concerns

Students are advised to discuss any questions or concerns that may arise during the course with the Course Coordinators, Jason Muhitch and Michelle Messmer, who will be overseeing attendance and student participation.


Course Coordinators:

Drs. Jason Muhitch & Michelle Messmer

Jason Muhitch, Ph.D.
Department of Urology
Phone: (716)845-7180
CGP Rm L5-143

Michelle Messmer, Ph.D.
Department of Immunology
Phone: (716)845-3352
CGP Rm L5-139

Credit Hours: 
3:00 pm to 5:00 pm





August 26

No lecture; assign review articles


September 2

Heat Shock Proteins

Michelle Messmer

Primary Article

Review Article


September 9

Cytokine Microenviroment in Tumor

Dan Fisher



September 16

CRISPR Technology & Novel Tumor Models

Scott Olejniczak

Paper 1

Paper 2


September 23  

Oncolytic Virotherapy for Cancer Treatment

Danuta Kozbor

Paper 1

Paper 2


Septmeer 30

Multiple Myeloma

Sarah Holstein


October 7

Adoptive T cell Transfer for Cancer Therapy

Ricahrd Koya

Paper 1

Paper 2

Paper 3

October 14

Dendritic Cells & Cancer Immunotherapy

Aimin Jiang


October 21

Monocyte/Macrophage Plasticity in the Tumor Microenviroment

Jason Muhitch

Review Article

Primary Paper


October 28       

No Class; Upstate Immunology Conference (10/25-10/28)  

November 4

Allogeneic Hematopoietic Cell Transplantation

Xuefang Cao

Paper 1

Paper 2

November 11


November 18

Student Presentations

1. Riddhi Mahapatra

2. Tiffany Emmons

3. Sean Colligan

November 25

No Class; Thanksgiving  

December 2

Student Presentations

Ethics Discussion

1. Shivana Maharaj

2. Guanxi Qiao (Christina)

Elizabeth Repasky

December 9

No Class; Final Exam Week