Description

The Biostatistics Resource ensures that biostatistical, bioinformatics and biomathematical support is readily available to basic, clinical and population-oriented RPCI collaborators. Services include exploratory data analysis; grant writing (statistical methods sections); hypothesis formulation; experimental design; fitting models to data; simulating data from models; developing customized data mining software and developing novel methods based on emerging technologies (.e.g. cutting edge microarray platforms, computer intensive statistical methods).

Statistical Genetics & Genomics Resource

The goal of BAVR group, headed by Dr. Jeffrey Miecznikowski Ph.D., is to develop a sustainable and nationally recognized Biotechnical Analytic Resource for Roswell Park Cancer Institute (RPCI). The mission of the analytic resource will be to develop novel statistical methodologies and software applications for the analysis of data generated by experiments utilizing emerging biotechnologies. Further, BAVR will assist in the development and optimal design of nascent biotechnologies at RPCI.

The specific objectives for the analytic resource include developing custom quality control metrics and custom diagnostics with the ability to detect failures in high throughput technologies utilized at RPCI. Further, BAVR will develop and advance modeling tools and methods for normalization and standardization of biological signals.

The mission of the visualization aspect will be to develop custom visualizations for large high throughput biological datasets. The visualization aspect of BAVR is intimately connected with the analytics mission since developing QC methods and normalization methods will require novel methods to visualize the data and assess the quality of the analytics from biological signals.

A major strength for the BAVR is the ready access to the resources and expertise of the University at Buffalo’s Center for Computational Research (CCR). Specifically BAVR will utilize the CCR’s state of the art parallel computing as well as their extensive expertise in the reconstruction of biological imaging data.

Location

New York State Center of Excellence 

Equipment

• Microcomputer Workstations
• Statistics / Mathematics / Graphics Software

Operating Schedule

Weekdays, 9am - 5pm

Using the Facility

Investigators should contact the team regarding use of the collaborative services of the Biostatistics Resource.

Services

The Biostatistics Resource provides assistance in statistical design of studies, design of data collection instruments, analysis of research data and publication of findings.

Scheduling

Priority is given to investigators who have outside funding, an approved clinical trial, or are preparing protocols and/or grant applications.

Contact Information

Alan Hutson, PhD., Chair  (716) 881-8951

Pamela Jarrett, Administrative Aide (716) 881-8950